The management of patients with chronic myeloid leukemia (CML) during pregnancy has became recently a matter of continuous debate.The introduction of the Tyrosine Kinase Inhibitors (TKIs) in clinical practice has dramatically Respiratory Accessories changed the prognosis of CML patients.Patients diagnosed in chronic phase can reasonably expect many
Regulatory considerations for biosimilars
Currently there is considerable interest in the legislative debate around generic biological drugs or "biosimilars" in the EU and US due to the large, lucrative market that it offers to the industry.While some countries have issued a few regulatory guidelines as well as product specific requirements, there is no general consensus as to a single, si
A possible way to naturalize the human soul
One of the most basic linguistic principles (or parameters, according balicki stick to some) is used to point to a likely necessary (though, probably, not sufficient) condition of human uniqueness (i.e.being able to speak, communicate complex messages, have religious feelings, indulge in art and humour, and so on) which has been conceptualised eith
Separate-layer balanced waterflooding development technology for thick and complex carbonate reservoirs in the Middle East
Based on the Party waterflooding development in carbonate reservoirs in the Middle East, in order to solve the problem of the poor development effects caused by commingled injection and production, taking the thick bioclastic limestone reservoirs of Cretaceous in Iran-Iraq as an example, this paper proposes a balanced waterflooding development tech
A new two-fingered dinosaur sheds light on the radiation of Oviraptorosauria
Late Cretaceous trends in Asian dinosaur diversity are poorly understood, but recent discoveries have documented a radiation of oviraptorosaur theropods in China and Mongolia.However, little work has addressed the factors that facilitated this diversification.A new oviraptorid from the Late Cretaceous of Mongolia sheds light on the evolution of the